Stochastic modelling and simulation of PTEN regulatory networks with miRNAs and ceRNAs
نویسندگان
چکیده
Abstract In this work, three genetic regulatory networks are considered, that model the post–transcriptional regulation of PTEN onco–suppressor gene, mediated by microRNAs and competitive endogenous RNAs, in glioblastoma multiforme, most severe brain tumours. We simulate solutions resulting stochastic differential systems discuss effects miRNA–fashioned on expression.
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ژورنال
عنوان ژورنال: Annali Dell'universita' Di Ferrara
سال: 2022
ISSN: ['1827-1510', '0430-3202']
DOI: https://doi.org/10.1007/s11565-022-00416-7